Prof. Nishith Kumar Pal

Professor and Head, Dept. of Microbiology, Maldah Medical college, (Maldah Town, West Bengal)


Address: Abhyuday Housing Society (Near Ruby Hospital), Ruby Golpark Kolkata 700107.

Education:

Name

University/Board

% of
marks

Academic
Distinction

Chances
taken

Year of
passing

1st MBBS Part- I

Calcutta University

76.5

None

Single

1973

1st MBBS Part- II

Do

73.5

Do

Do

1975

Final MBBS Part-I

Do

53.5

Do

Do

1976

Final MBBS Part-II

Do

65.6

Do

Do

1977

Final MBBS Part-III

Do

59.88

Do

Do

1978

D.C.P.

Faculty of Trop.’ Med’ & Hygiene ,Govt. Govt. of W.B.

68

Do

Do

1982

M.D. Microbiology

Calcutta University

58

Do

Do

1989

Professional experience:

From

To

Institution

Position

01. 07. 1983

31. 10. 1986

N. B. Medical College, Department of Microbiology

Demonstrator

31. 05. 1990

29. 05. 1993

Calcutta School of Tropical Medicine, Department of Bacteriology and Serology

Lecturer

29. 05. 1993

24. 05 1995

Do

Assistant Professor

24. 05 1995

24. 05 1997

Do

Reader

17.07.1998

21.08.2008

Do

H.O.D.

24. 05. 2000

Till date

Do

Professor

21.8.08

21.11.2011

Microbiology, I.P.G.M.E&R.

H.O.D.

21.11.2011

Till date

Maldah Medical College. Dept. of Microbiology

H.O.D.


Projects handled:

  1. HIV/STD prevalence amongst G&O clinic in Calcutta- part of a multicentric study.Funded by I.C.M.R.
  2. Scientific validation of traditionally used medicinal plants of India against multi drug resistant clinical isolates.Funded by I.C.M.R.
  3. WHO- through AIIH&PH: “Base line data of HIV/STD amongst CSWs in Calcutta”.
  4. DBT: “Modification of conventional liquid medium for rapid detection of growth of Mycobacterium tuberculosis.”
  5. DAE/BRNS: “Signal transduction mechanism during host-pathogen interaction: Special emphasis on the change in Th1-Th2 cytokine response in macrophages from different age groups infected with Mycobacterium tuberculosis”.

 

Salient achievements:


Dr. N. K. Pal worked in depth with many new findings on the immune responses in tuberculosis. The data from his research revealed that variation in the innate immune response correlate with the different clinical outcome of tuberculosis. This gives a lead to identify the specific immune markers for better comprehension of the individual cell function and immunopathological mechanisms associated with different clinical forms of the disease.
He also worked with the molecular techniques for the detection and characterization of drug resistance in mycobacteria in the sputum samples of clinically confirmed tuberculosis. He demonstrated the great potential of molecular techniques (RFLP, MAS-PCR) in accurate diagnosis of tuberculosis.

His work on traditionally used various medicinal plants of India has been found as great therapeutic tool against multi drug resistant organisms.

Top five research papers:
1.Chakraborty U, Goswami A, Saha S, Mukherjee T, Dey SK, Majumdar S, Pal NK.
Tumour necrosis factor-alpha and nitric oxide response in different categories of tuberculosis patients. Int J Tuberc Lung Dis. 2013 Apr;17(4):505-10. doi: 10.5588/ijtld.12.0196.
2. Chowdhury IHSen ABahar BHazra AChakraborty UChoudhuri SGoswami APal NKBhattacharya B. A Molecular Approach to Identification and Profiling of First-Line-Drug-Resistant Mycobacteria from Sputum of Pulmonary Tuberculosis Patients. J. Clin. Microbiol. 03/2012; 50(6):2082-4. 
3 .Nivedita Majumdar, Surajit Bhattacharya, Ranadhir Dey, Suchandra Bhattacharya (Majumdar), Pal Nishith K, Subrata Majumdar. Arabinosylated lipoarabinomanan modulates the impaired cell mediated immune response in Mycobacterium tuberculosis H37Rv infected C57BL/6 mice. Microbes and Infection.2008; 10(4):325-454.
4. K.D. Thomas, Airody Vasudeva Adhikari, Imran H. Chowdhury, E. Sumesh, Nishith K. Pal. New quinolin-4-yl-1,2,3-triazoles carrying amides, sulphonamides and amidopiperazines as potential antitubercular agents. European Journal of Medicinal Chemistry, Volume 46, Issue 6, June 2011, Pages 2503-2512.
5. Majumdar, N., Bhattacharjee, S., Dey, R., Majumdar Bhattacharyya, S., Pal, N K. and Majumdar, S Arabinosylated lipoarabinomannan modulates the impaired cell mediated immune response in Mycobacterium tuberculosis H37Rv infected C57 BL/6 mice (2008). Microbes and Infection. Vol. 10(4), 349-357.

 

Awards and recognitions:

    1. WHO Fellowship, 1996.

Technologies developed:
The conventional media for the growth of mycobacterium has been modified with different fluorescent dyes for the rapid growth detection of mycobacterium.

Professional affiliations:

    1. Life member of IAMM.
    2. Life member IMA